Deliriants

The deliriants (or anticholinergics) are a special class of dissociative which are antagonists for the acetylcholine receptors (unlike muscarine and nicotine which are agonists of these receptors). Deliriants are considered to be true hallucinogens as users will have conversations with people who aren't there, or become angry with a 'person' mimicking their actions, not realizing it is their own reflection in a mirror (which could be dangerous if they became aggressive towards a glass mirror). While the regular dissociatives can produce effects similar to lucid dreaming (where one is consciously aware they are dreaming), the deliriants have effects akin to sleepwalking (where one doesn't remember what transpired during the experience).

Included in this group are such plants as deadly nightshade, mandrake, henbane and datura, as well as a number of pharmaceutical drugs when taken in very high doses such as the antihistamine diphenhydramine (Benadryl) and the antiemetic dimenhydrinate (Dramamine or Gravol).

In addition to the danger of being far more "out of it" than with other drugs, and retaining a truly fragmented dissociation from regular consciousness without being immobilized, the anticholinergics are toxic, can cause death due to overdose, and also include a number of uncomfortable side effects. These side effects include dehydration and mydriasis.