Headshop Class B information Dihydrocodeine, DHC & Paracodeine info head shop

Headshop Class B information Dihydrocodeine, DHC & Paracodeine

Dihydrocodeine, also called DHC and Paracodeine and by the brand names of SS Bron, Drocode, Paracodin, Codidol, Didor Continus, Dicogesic, and DF-118 amongst others, is a semi-synthetic opioid analgesic prescribed for postoperative pain, severe dyspnea, or as an antitussive. Dihydrocodeine tartrate is also present in co-dydramol. In some countries, controlled-release dihydrocodeine and/or the immediate release forumulations are used as an alternative to methadone in treatment of opioid dependency and addiction.

Commonly available as tablets, solutions, elixirs, and other oral forms, dihydrocodeine is also available in some countries as an injectable solution for deep subcutaneous and intra-muscular administration. Intravenous administration could be dangerous due to pulmonary oedema and the potential of anaphylaxis as it is with codeine. At one time in the past and possibly now, dihydrocodeine suppositories also existed.

Dihydrocodeine is used as an alternative to or incrementation on codeine for the above mentioned spectrum of situations. It is available as the following salts, in rough descending order of frequency of use: bitartrate, phosphate, hydrochloride, tartrate, hydroiodide, methyliodide, hydrobromide, and sulphate. The salt to free base conversion factors are 0,67 for the bitartrate, 0,73 for the phosphate, and 0,89 for the hydrochloride.

Dihydrocodeine was developed in Germany during the early 1900s during the great search for more effective antitussives, and is similar in chemical structure, pharmacological activity, and potency as codeine. Depending on individual metabolism, dihydrocodeine is 100 to 150 percent as strong as codeine. Although dihydrocodeine does have extremely active metabolites, in the form of dihydromorphine and dihydromorphine-6-glucuronide (100x more potent), these metabolites are produced in such small amount that they do not have clinically important effects.

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